Abstract
The levels of ten trace elements in the range Ca to As in the scalp hair of schizophrenics were analyzed using Particle Induced X-ray emission (PIXE) technique. Thirty males and females with a confirmed diagnosis of schizophrenia and an equal number of age-matched controls of both genders were chosen. The samples were excited with a proton beam of 2.5 MeV and spectra were scanned by a Si (Li) detector. The findings revealed a statistically significant difference in the concentration of six trace elements (Ca, Zn, Se, Mn, Fe, Ni, and Cu) in scalp hair of schizophrenia patients compared to controls, implying a disruption in the homeostasis of these elements. A plausible correlation of this imbalance with the etiology and pathology of schizophrenia is discussed.
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