Abstract

Experiments were made by Porter and Silber's method in N. A. Yudaev and Yu. A. Pankov's modification to establish the normal level of 17-hydroxycorticosteroids in the blood plasma of monkeys. The concentration of 17-hydroxycorticosteroids in male rhesus macaques was on the average 34±1.3 mg %, in females −44±1.2 mg %; in male and female hamadryads −41±1.5 mg % and 52±1.5 mg % respectively. Variable reaction of the adrenal cortex to intravenous injection of ACTH was found in different species of monkeys, in rhesus macaques the maximum increase in the amount of 17-hydroxycorticosteroids was registered one hour after the injection of the preparation, in hamadryads-in two hours. Nembutal anesthesis presents the development of the stress condition. It was found that the neuro-emotional strain in monkeys brings about a marked increase in the hormonal function of the adrenal cortex.

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