Level of cardiac troponin I in patients with myocardial infarction in front and back on the sport

Abstract

Objective To study whether an increase of cardiac troponin Ⅰ(cTnI) can be observed after symptom - limited exercise and an exercise training session in patients with myocardial infarction(MI). Methods Twenty eases of MI and moderate heart failure were compared with 15 patients with MI and mild heart failure and 10 normal subjects without heart failure. All subjects underwent a symptom - limited test and an exercise training session at > 80% of maximal heart rate over dine 30 minutes. The plasma cTnI level were measured at baseline,after symptom - limited exercise hourly for 5 hours,and 1 to 5 hours after train-ing. Results Patients with MI and moderate heart failure showed an increase of cTnI from(38±19) pg/ml to (75±29) pg/ml(P<0.01) after symptom - limited exercise. Five patients with moderate and two patients with mild heart failure and normal cT-nI values at rest showed the increase of cTnI above 100 pg/ml after acute exercise but not after training. Subjects without heart failure had lower cTnI levels at rest and significantly lower values after symptom - limited exercise and training(P<0.05 for each). Conclusion Patients with MI and symptomatic heart failure show an increase of cTnI after symptom - limited exercise at levels that indicate minor myocardial damage. The prognostic impact of this finding should be further investigated. Key words: Myocardial infarction; Heart failure; Exercise test; Cardiac troponin Ⅰ