Abstract
High intensity focused ultrasound (HIFU) is a minimally invasive treatment option that might be considered in the management of localized prostate cancer. It is a well-tolerated treatment with few minor urologic complications and no major toxicities. In this paper, we report to our knowledge the first case of levator ani necrosis in a patient treated with HIFU, manifesting as sturdy perineal pain, which took years of NSAID intake and serial MRIs to demonstrate partial improvement. Therefore, we regard HIFU as a serious potential treatment option that still requires longer follow-up data before its approval in the personalized treatment panel of prostate cancer.
Highlights
In view of the increased incidence of prostate cancer patients, the concept of personalized treatment has been drastically evolving
High intensity focused ultrasound (HIFU) is a minimally invasive treatment option that might be considered in the management of localized prostate cancer
We report to our knowledge the first case of levator ani necrosis in a patient treated with HIFU
Summary
In view of the increased incidence of prostate cancer patients, the concept of personalized treatment has been drastically evolving. High intensity focused ultrasound (HIFU) is a minimally invasive treatment option that might be considered in the management of localized prostate cancer. This technique was developed in the 1990s to destroy the prostate tissue with high intensity ultrasound waves via a transrectal probe. A coagulation necrosis is induced by the thermal and mechanical effects of the transmitted waves and the prostatic tissue is subsequently destroyed and replaced by a scar tissue within weeks [2].
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