Abstract

Introduction: Nephrotic syndrome (NS) is the commonest glomerular disorder in childhood. Cyclosporine-A (CsA) has been used widely for children around puberty with moderate to severe steroid dependency. As long term CsA is potentially nephrotoxic, continuing CsA beyond 5 years is not recommended. This retrospective study was conducted to evaluate the outcome of different strategies when withdrawing CsA in patients after 5 years of therapy.

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