Abstract
Microvesicles are released from the plasma membrane of various cell types, can be taken up by other cells, and can transport membrane proteins and cytosolic contents between cells. Kahn etal. demonstrate that leukocyte-derived microvesicles bearing B1-kinin receptors are enriched in the plasma of vasculitis patients and dock on endothelial cells in the glomerulus. Cell culture experiments suggest that B1-receptors transferred by these microvesicles are functionally active on acceptor cells.
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