Abstract
Abstract 1. Normnal and irradiated rats underwent periods of cross-circulation with Shay granulocytic chloroleukemic rats. 2. The leukemic white blood cells disappeared rapidly from the arterial blood of the irradiated rat at a rate approximately identical with that of the removal of cross-transfused normal leukocytes. 3. Many leukemic cells remained in the arterial blood of normal recipent rats during the 90 miniute observation time after cross-circulation. 4. It was postulated that leukocytes transfused its rats by this method remain viable. In the irradiated leukopenic recipient, the rapid arterial blood removal rate of transfused cells may represent distribution in a depleted total body leukocyte "pool." Similarly, distribution may occur more slowly in normal animals with normally saturated tissue stores of leukocytes. 5. There was no indication that a large dose of total body irradiation increased the capacity of the reticulo-endothelial system to remove transfused leukocytes from circulation.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
