Abstract

Leukemia inhibitory factor (LIF), has been cited to play important role in embryo development and implantation. This pleiotropic cytokine affects a range of events in implantation, such as, endometrial receptivity, embryo-endometrial interaction, stromal decidualization, trophoblast invasion and blastocyst development. Lower levels of LIF have been found in blood and endometrial tissue of women with recurrent pregnancy loss (RPL). The objective of this study was to assess the levels of LIF in plasma of women with RPL and healthy fertile females.

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