Abstract

SummarySpecific involution of the thymus resulted from pyridoxine deficiency in rats and could be distinguished from the atrophy resulting from inanition alone. Inanition induced lymphopenia of the same degree in young and adult pyridoxine-deficient animals and their respective pair weighed controls. Granulocytosis occurred only in the pyridoxine-deficient young and adult animals. All blood and thymus changes were rapidly restored to normal following realimentation of the deficient and pair weighed adult animals.

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