Abstract

The article describes a case of Letterer-Siwe disease (Langerhans cells histocytosis, histiocytosis X) in a 1-year-old infant, presents the authors` own observations focusing on the macroscopic and histological picture of skin lesions. The work also notes difficulties of diagnosis of this disease. Reliable morphological features of Letterer-Siwe disease were revealed during the histologic examination of the skin.

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