Abstract
To the Editor: In their Letter to the Editor, Drs Berenfeld, Pertsov, and Jalife1 suggest that our recent article entitled “The Distribution of Refractory Periods Influences the Dynamics of Ventricular Fibrillation”2 characterized the nature of wave organization during fibrillation. They also state that our study “provides important and useful information, particularly in regard to the existence of action potential duration gradients during VF.” With respect to these comments, we should clarify that we did not focus on the nature of wave organization in ventricular fibrillation (VF), nor did we show the existence of action potential duration (APD) gradients during VF. We correlated APD gradients measured in hearts with a normal rhythm (either paced or sinus rhythm) with the distributions of mean activation intervals and fast Fourier transform (FFT) spectra around the epicardium from the same hearts in VF. The main conclusion is stated in the title of the article.2 Berenfeld et al1 criticized the study claiming that we did not address technical issues and overinterpreted our data. Surprisingly, the issues that they raised and their concerns over the …
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
