Abstract

Drs. Stiehm and Clatanoff (Pediatrics, 43: 770, 1969) report a high incidence of split products of fibrin (SPF) in the cord blood of healthy newborn infants. This is contrary to our own experience which had indicated the presence of SPF in only 5% of healthy newborns. We use a hemagglutination inhibition technique which is at least as sensitive as the tube precipitin assay employed by Drs. Stiehm and Clatanoff. The two methods differ in one important aspect, however; we have tested cord blood drawn into a mixture of sodium citrate and epsilon amino-caproic acid to inhibit in vitro fibrinolysis.

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