Letter to the editor

Abstract

Cytometry Part B: Clinical CytometryVolume 70B, Issue 2 p. 106-106 Letter to the EditorFree Access Letter to the editor First published: 02 February 2006 https://doi.org/10.1002/cyto.b.20081AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Response from authors to the letter: We appreciate the comments by Dr. Dignat-George related to our recent review article (1). The 1991 publication by Dr. Dignat-George and colleagues (2) was a seminal study in the field of circulating endothelial cells and nearly a decade ahead of most other such studies. These investigators should be lauded for this pioneering work and their continued studies. In concert with Dr. Dignat-George, we echo again, the need for standardization of CEC assays. While our group believes that multiparametric flow cytometry is best suited to this end, due to inherent cell loses which accompany multistep techniques, we remain open to alternative approaches. We look forward to discussing these matters at the upcoming EWGCA meeting in Greece. Additionally, there will be a post-meeting “CEC Working Group Session” on Wednesday October 19, 2005 in Savannah, Georgia, immediately following the meeting of the Clinical Cytometry Society. This working group session is free to all who attend the CCS meeting. Working together, we believe that the EWGCA and CCS will help develop standard approaches to CEC enumeration that will be crucial for the successful use of this most interesting biomarker of disease. LITERATURE CITED LITERATURE CITED 1 Khan SS, Solomon MA, and McCoy JP. Detection of circulating endothelial cells and endothelial progenitors cells by flow cytometry. Cytometry B: Clin Cytometry 2005; 64: 1– 8. Wiley Online LibraryPubMedWeb of Science®Google Scholar 2 George F et al. Cytofluorometric detection of human endothelial cells in whole blood using S-Endo 1 monoclonal antibody. J Immunol Methods 1991; 139: 65– 75. CrossrefCASPubMedWeb of Science®Google Scholar Volume70B, Issue2March 2006Pages 106-106 ReferencesRelatedInformation