Abstract
Much anxiety has been engendered in clinicians and parents by reports of serious brain damage due to phenobarbital given to young rodents in doses far higher than those clinically used for children.1,2 Our study, and that of Camfield et al3 better enables parents and pediatricians to evaluate the degree of risk to cognitive development with continuous phenobarbital at conventionally used dosage. We would welcome the publication of any of Schain's data, using whichever tests he prefers, which might give further information about the effect of both phenobarbital and febrile seizures on intellectual development in children.
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