Abstract
We appreciate the comments of Sacher et al and share their view that the presence of anti-hepatitis Be in a hepatitis B surface antigen-positive mother does not prevent vertical transmission of either icteric or anicteric hepatitis B. Since publication of our paper1 we have identified two additional infants, born to HBeAg-positive and anti-HBe-positive carrier mothers, in whom evidence of hepatitis B transmission was identified. In one case, transient antigenemia was detected and was subsequently followed by the appearance of anti-HBe.
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