Letter to the Editor: Coronavirus Disease 2019-Related Liver Injury and Clinical Outcomes: Does It Really Exist?

Abstract

We read with interest the study by Lei and colleagues on the association between markers of liver injury and mortality in coronavirus disease 2019 (COVID-19) in China. The authors have painstakingly collated data from a large number of COVID-19 patients from multiple centers across Wuhan. They found that an increase in aspartate aminotransferase (AST) and its dynamicity correlated with COVID-19-related liver injury and patient outcomes. They concluded that the dynamic patterns of liver injury indicators, represented by AST, correspond with COVID-19-related liver injury.