Abstract
I read with great interest the article by Kananen and colleagues that contributed greatly to our understanding of the relationship between body mass index (BMI), nutrition status, and in-hospital mortality among older adults hospitalized for coronavirus disease 2019 (COVID-19) [[1]Kananen L. Eriksdotter M. Boström A.M. Kivipelto M. Annetorp M. Metzner C. Cederholm T. Body mass index and Mini Nutritional Assessment-Short Form as predictors of in-geriatric hospital mortality in older adults with COVID-19.Clin Nutr. 2021; Abstract Full Text Full Text PDF PubMed Scopus (2) Google Scholar]. The authors found that being underweight (BMI <18.5) and malnutrition increased the risk of in-hospital mortality after adjusting for some potential confounding factors, but being overweight and obese were not found to be associated with an increased risk of mortality in COVID-19 patients. Although there are studies examining the relationship between BMI and COVID-19 related mortality in the literature, this study is of paramount importance regarding the study population which consists of very old and people living with frailty. However, there may be some residual confounding factors to consider when interpreting the results of the study. First, the authors didn't provide the detailed information about the nutrition therapy of the patients during the hospitalization. In a randomized multicenter study in which the majority of the study population consisted of older adults aged 75 years and older when compared to standard hospital meal alone, to reach protein and caloric goals in medical inpatients at nutritional risk early use of individualized nutritional support decreased the risk of mortality within 30 days (OR: 0.65, (0.47–0.91); p < 0.011) [[2]Schuetz P. Fehr R. Baechli V. Geiser M. Deiss M. Gomes F.,. Mueller B. Individualised nutritional support in medical inpatients at nutritional risk: a randomised clinical trial.Lancet. 2019; 393: 2312-2321Abstract Full Text Full Text PDF PubMed Scopus (242) Google Scholar]. Second, among hospitalized older adults living with frailty, the co-existence of malnutrition and delirium could be high [[3]Rosted E. Prokofieva T. Sanders S. Schultz M. Serious consequences of malnutrition and delirium in frail older patients.J Nutr Gerontol Geriatr. 2018; 37: 105-116Crossref PubMed Scopus (9) Google Scholar]. It is well-known that delirium is a frequent condition in older adults admitted for COVID-19 [[4]Marengoni A. Zucchelli A. Grande G. Fratiglioni L. Rizzuto D. The impact of delirium on outcomes for older adults hospitalised with COVID-19.Age Ageing. 2020; 49: 923-926Crossref PubMed Scopus (37) Google Scholar]. In a recent study, among patients aged 70 years older hospitalized for COVID-19, according to the regression analysis adjusted for age, gender, number of chronic disease, frailty, and arterial blood oxygen saturation at admission, it was found that patients with delirium were four times more likely to die during the hospital stay compared to those without delirium [[4]Marengoni A. Zucchelli A. Grande G. Fratiglioni L. Rizzuto D. The impact of delirium on outcomes for older adults hospitalised with COVID-19.Age Ageing. 2020; 49: 923-926Crossref PubMed Scopus (37) Google Scholar]. In sum, this is a fascinating report, and it provides excellent insight into the prognostic value of BMI and malnutrition regarding in-hospital COVID-19 related mortality among older adults living with frailty. However, clarifying the above-mentioned points will help the readers to interpret the study findings accurately. Response to Letter to the Editor: Comment on “Body mass index and Mini Nutritional Assessment-Short Form as predictors of in-geriatric hospital mortality in older adults with COVID-19” (by Café Balcı, MD, Hacettepe University Faculty of Medicine Department of Internal Medicine Division of Geriatric Medicine)Clinical NutritionVol. 41Issue 2PreviewThank you very much for the opportunity to respond to the Letter by MD Cafer BALCI on our article concerning the relationships between mortality and nutritional status and BMI in older patients hospitalized for COVID-19 [1]. Full-Text PDF
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.