Abstract
Renal function and electrolyte disturbances in normocalcaemic and hypercalcaemic patients treated with mithramycin
Highlights
To our knowledge no precise variations of sodium, chloride, magnesium study of renal function has been carried out and phosphorus throughout the infusion in the course of the administration of of Mithramycin but plasma potassium was reduced in our 17 patients
A loading reported by Baum (1968) and by Ryan, dose of Inulin and P.A.H. was given at Schwartz and Northrop (1970) but no time to, The serum concentrations of Inulin systematic study of the variations in plasma and P.A.H. were kept constant by main- potassium had been undertaken in their tenance infusion at a constant rate of patients
The fall in serum calcium of urine were collected correspond- varies in degree, is transient and often ing to successive 10 min periods and two insufficient to rectify any marked hypersamples of blood (b1 and b2) were taken at calcaemia
Summary
Have noted the possibility of renal 3. To our knowledge no precise variations of sodium, chloride, magnesium study of renal function has been carried out and phosphorus throughout the infusion in the course of the administration of of Mithramycin but plasma potassium was reduced in our 17 patients Malignant disease, 8 of them having hyper- This variation in plasma levels was not calcaemia, were treated with an intravenous accompanied by an increase of the urinary perfusion of Mithramycin.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
