Abstract
To the Editor.— Naloxone hydrochloride (Narcan orn-allyloxymorphone) antagonizes the pharmacologic effects of narcotics like nalorphine and levallorphan. But unlike the other two antagonists, naloxone does not by itself cause respiratory depression or other narcotic effects.1Naloxone hydrochloride is relatively free of adverse side effects; however, a high incidence of nausea and vomiting (90%) has been reported after its administration.2Systolic blood pressure usually falls slightly after giving a narcotic antagonist.2The purpose of this letter is to describe a patient who developed a paradoxical hypertensive reaction to naloxone hydrochloride. Report of a Case.— A 51-year-old man was admitted to the hospital for coronary artery bypass grafting. He had a previous history of mild essential hypertension, type IV hyperlipidemia, and mild diabetes mellitus. On Aug 7, 1973, the patient underwent cardiac surgery, assisted by cardiopulmonary bypass under morphine-nitrous oxide-oxygen anesthesia. The procedure was uneventful, requiring two
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
