Abstract
I have read “Early Dual Versus Mono Antiplatelet Therapy for Acute Non-Cardioembolic Ischemic Stroke or Transient Ischemic Attack: An Updated Systematic Review and Meta-Analysis” by Wong and colleagues1 with great interest. In this meta-analysis, the authors included 14 randomized, controlled trials (9012 patients) comparing dual versus mono antiplatelet therapy for acute noncardioembolic ischemic stroke or transient ischemic attack (TIA) within 3 days of ictus. They found that when compared with mono antiplatelet therapy, dual therapy was associated with a reduction in stroke recurrence, and composite vascular events, but without a significant increase in the risk of major bleeding. As the authors state, …
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