Abstract
Recently, Bittl1 et al performed a network meta-analysis of indirect evidence using Bayesian methods and proved that percutaneous coronary intervention (PCI) improves survival for patients with unprotected left main coronary artery disease compared with medical therapy. However, we are concerned about the validity of the network meta-analysis. Network meta-analysis is a statistical method for combining both direct and indirect evidence from multiple trials to obtain a single consistent quantitative synthesis. The key assumption underlying network meta-analysis is exchangeability of the trials or the …
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