Letter by Stefan et al Regarding Article, “Impact of Body Mass Index and the Metabolic Syndrome on the Risk of Cardiovascular Disease and Death in Middle-Aged Men”

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To the Editor: In the recent article by Arnlov et al,1 middle-aged men with the metabolic syndrome had an increased risk of cardiovascular events. An increased risk was also found for overweight and obese men without the metabolic syndrome, as defined by Arnlov et al.1 Therefore, it was concluded that being overweight and obese without metabolic derangements is not benign. The question of whether some overweight or obese subjects are protected from cardiovascular disease and death is important particularly because the resources used to prevent these events often involve lifelong lifestyle and/or pharmacological intervention, which are expensive and …