Abstract

We read with great interest the article by Madder et al1 entitled “Multimodality Intracoronary Imaging With Near-Infrared Spectroscopy and Intravascular Ultrasound in Asymptomatic Individuals With High Calcium Scores”. The study assessed the frequency of lipid-rich plaque in asymptomatic patients with coronary artery calcium scores >300 Agatston units. The authors concluded that in patients mostly on statins, coronary artery calcium scores >300 Agatston units correlated with total plaque volume but not lipid-rich plaque and it is lipid-rich plaque that underlies the most of the acute events. …

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