Abstract

We read with great interest the recently published article by Wu et al1 in which the authors investigated the associations of circulating omega-6 (ω-6) polyunsaturated fatty acids (PUFAs), including linoleic acid, γ-linolenic acid, dihomo-γ-linolenic acid, and arachidonic acid, with total and cause-specific mortality in a community-based US cohort. They concluded that high circulating linoleic acid, but not other ω-6 PUFAs, was inversely associated with total and coronary heart disease mortality in older adults. However, we think that there are some points that should be emphasized about this …

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