Abstract
To the Editor: The aims of this letter are to congratulate the authors for the results of Conduit Artery Function Evaluation (CAFE) study1 and to challenge the difference in heart rate as a preponderant explanation for the differences in central systolic blood pressure (SBP) between amlodipine- and atenolol-based treatment. On the basis of the Regression of Arterial Stiffness in a Controlled Double-Blind Study (REASON), in which perindopril plus indapamide (Per/Ind) was compared with atenolol alone for 12 months in hypertensive subjects,2 …
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