Abstract

We read with interest the recent article by Flaherty et al1 published in Circulation Research . In the analysis of this retrospective, single-center study, patients were randomized into 2 groups, percutaneous left ventricular assist device (pLVAD) supported and unsupported undergoing high-risk percutaneous coronary intervention. All patients had severely reduced ejection fractions (<35%) and high-risk clinical features. Because acute kidney injury is quite common in this cohort, Impella 2.5 pLVAD support was independently associated with a significant reduction in the risk of …

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