Abstract

To the Editor: Chiao et al gained further insights of the role of plasma biomarkers in association to cardiac aging phenotypes. The authors observed significantly higher plasma levels of inflammatory markers in the senescent compared with the adult C57/BL6J mice. Among them, matrix metalloproteinase-9 (MMP9) correlated with the increase in end-diastolic dimensions that occurred with senescence. Dual labeling …

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