Abstract
The study by Miller et al1 evaluated cardiac magnetic resonance (CMR) techniques in the assessment of myocardial extracellular volume (ECV). Two commonly used measures of ECV expansion, namely dynamic-equilibrium CMR and isolated measurement of postcontrast myocardial T1 time, were compared with histological analysis of the explanted hearts of transplant recipients. Both measures proved remarkably similar in their correlation with histology on a within-subject basis, with r values of a similar absolute magnitude (≈0.7). However, when correlation was sought on a between-subject basis, dynamic-equilibrium CMR demonstrated a significant correlation with histology ( r value 0.95; P =0.004), whereas postcontrast T1 time did not ( r value …
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