Abstract
With interest we read the article by Patel et al1 about the effect of cerebral microbleeds (CMBs) on several cognitive domains in patients with symptomatic cerebral small vessel disease. The purpose of the study was to determine associations between cognition and presence, number and location of CMBs, and whether associations were independent of other imaging markers of cerebral small vessel disease. A homogeneous group of patients with lacunar stroke with white matter lesions was included. The results showed that the number of CMBs was weakly related to executive function, but not to other cognitive domains. Strikingly, the relationship between CMBs and cognition has not been studied before in patients with lacunar stroke, so this study really adds to the existing literature. However, there are some issues we would …
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