Abstract

To the Editor: We read with great interest the article by Alberts et al1 on “Using Dabigatran in Patients With Stroke: A Practical Guide for Clinicians.” The authors provided an excellent review on dabigatran and the issues encountered in patients with stroke. One challenge with dabigatran is the treatment of acute ischemic stroke for which intravenous tissue-type plasminogen activator administration or endovascular cerebral intervention may be warranted. We recently had a 66-year-old female patient who had been taking 150 mg dabigatran orally twice daily for prevention of stroke in atrial fibrillation. Dabigatran was held 3 days before a cardiac ablation procedure but was resumed immediately after the ablation. Within 1 hour of the procedure, she developed an acute ischemic stroke of the right middle cerebral artery M1 artery on CT angiogram, which resulted in global aphasia …

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