Letter by Cameron et al Regarding Article, “Differential Impact of Blood Pressure-Lowering Drugs on Central Aortic Pressure and Clinical Outcomes: Principal Results of the Conduit Artery Function Evaluation (CAFE) Study”

Abstract

To the Editor: We read with interest the report of the Conduit Artery Function Evaluation (CAFE) study1 showing a difference in SphygmoCor-derived central systolic blood pressure (SBP) between the 2 arms of an Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) substudy (despite similar brachial blood pressure changes). We would make 3 points. First, the authors seem to have misinterpreted our work (authors’ Reference 53)2 as showing a “precision” of 1 mm Hg between calculated central aortic and directly measured SBP in the context of noninvasive studies. This figure relates to …