Abstract

To the Editor: We greatly appreciated the article by Miller et al.1 In contrast to several studies showing a major role of brain natriuretic peptide (BNP) as a predictor of adverse prognosis in heart failure,2,3 the study by Miller et al reported that elevated BNP at baseline was not significantly associated with outcome (primary end point: death/cardiac transplantation) in a cohort of 190 patients with New York Heart Association class III-IV heart failure who were followed up for 24 months, after adjustment for troponin T levels, …

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