Letter by Agostini et al Regarding Article, “Stent Thrombosis Late After Implantation of First-Generation Drug-Eluting Stents: A Cause for Concern”

Abstract

To the Editor: We appreciated the thorough review of Camenzind et al1 of late stent thrombosis in drug-eluting stents. Although we agree with their general message, we have concerns related to the hypothetical correlation purported by the authors between angiographic late lumen loss and clinical events, which is not evidence based. In particular, Figure 2 is not based on scientific data; the authors cite as its reference only an editorial.2 The J-curved relationship between late loss and clinical events is puzzling. Although some evidence exists that …