Abstract
Saccharomyces cerevisiae (wild-type strain 211) in a stationary phase was exposed to 12-MeV electrons over a dose range of 0. to 700 rads. In one set of experiments a first dose was given in air and a second 15 min later in nitrogen. In a second set of experiments, the first dose was in N/sub 2/ and the second in air. Survival curves were established by varying the size of the second dose. The shoulder of anaerobic curve was completely abolished by pre- irradiation with moderate doses in air. It is suggested that these results indicate a complete overlap of type O and N damage in both directions suggesting that both share a damage pathway in the cell, probably, but not necessarily acting on the same target molecule. (UK)
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