Abstract
Coronavirus infections of manifold origins have spread to date worldwide, causing severe respiratory diseases. Seven coronaviruses that infect humans have been recognized: HCOV-229E, HCoV-OC43, HCOV-NL63, HCOV-HKU1, SARS-COV, MERS-COV, and SARS-COV-2. Among them, SARS-COV and MERS-COV caused outbreaks in 2002 and 2012, respectively. SARS-COV-2 (COVID-19) is the most recently discovered. It has created a plain worldwide outbreak beginning in late 2019, leading to date to over 4 million cases globally.
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