Abstract
Let Sleeping Zebrafish Lie: A New Model for Sleep Studies
Highlights
The function of sleep is hotly debated, one thing is clear—we, and most other animals, cannot do without it
The sleepdeprived zebrafish showed a rebound effect: after being deprived of sleep for a time, they slept more, showing that their sleep is homeostatically regulated. When it came to the effects of light on zebrafish sleep, the authors discovered a marked difference from mammalian sleep
When zebrafish that had been kept in constant light for three days were returned to darkness, they slept normally, showing no compensatory increase in sleep
Summary
The function of sleep is hotly debated, one thing is clear—we, and most other animals, cannot do without it. Yokogawa et al describe how zebrafish sleep, finding both striking similarities to mammalian sleep and its regulation and intriguing differences. By using electrical stimulation to prevent the fish from sleeping, the authors found another similarity between mammalian and zebrafish sleep.
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