Abstract

Let's talk about flux or the importance of (intracellular) reaction rates.

Highlights

  • The physiology of cells, determined by all extracellular production and consumption rates, intracellular reaction rates and the growth rate, is of fundamental interest in such different fields of the life sciences as microbiology, biotechnology and medical applications. In this Crystal Ball, I emphasize the importance of metabolic reaction rates, that is fluxes, for our understanding of metabolic network operation and envisage a time in which fluxes can be changed at will

  • The ultimate goal of many fields of the life sciences is to understand cell physiology and the flux distribution, which characterizes the metabolic state of a cell

  • Fluxes are ignored, despite the ultimate goal implicitly being to understand metabolic network operation

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Summary

Introduction

The physiology of cells, determined by all extracellular production and consumption rates, intracellular reaction rates and the growth rate, is of fundamental interest in such different fields of the life sciences as microbiology, biotechnology and medical applications. In this Crystal Ball, I emphasize the importance of metabolic reaction rates, that is fluxes, for our understanding of metabolic network operation and envisage a time in which fluxes can be changed at will.

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