Lesions of the basal ganglia and frontal lobe promote differential impairment to working memory and learning ability

Junxia Ji,Danjun He,Zhongli Jiang

doi:10.15761/pmrr.1000144

Abstract

Lesions of the basal ganglia and frontal lobe promote differential impairment to working memory and learning ability

Highlights

Working memory is a system that can store and process information of the current task in the process of solving cognitive tasks
We found a marked decrease in the working memory of prefrontal lobe lesion (PLL) and basal ganglia lesion (BGL)
After training, BGL scores were significantly improved, while PLL were not. This indicated that unilateral BGL retained a degree of learning ability, and early cognitive training has the advantage of improving working memory and learning ability in patients with BGL

Summary

Introduction

Working memory is a system that can store and process information of the current task in the process of solving cognitive tasks. It plays an important role in leaning motor skills. It is important to appreciate that the memory system refers to the ability to temporarily maintain and manipulate information It is a combination of the traditional fields of attention, concentration, and short-term memory [2]. The memory system is the basis of many higher cognitive functions including learning, language understanding, reasoning and judgment. It can be used as a necessary means of occupational therapy. Numerous studies have shown that working memory required the participation of cortical networks and sub-cortical areas, especially the prefrontal cortex to perform a specific task [3,4]

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