Lesion sterilization and tissue repair therapy using GAM antibiotic paste

Abstract

Despite the efforts to prevent dental caries among children, premature loss of primary teeth due to pulp and periapical diseases is a common problem. The effect of this premature loss on the development of dentition is a matter of great interest. Importantly, the primary teeth are considered as natural space maintainers and therefore should be retained until their natural exfoliation. Based on these issues and concerns, the concept of “Lesion sterilization and tissue repair (LSTR)” therapy proposed by the Cariology Research Unit of the Niigata University School of Dentistry, would be preferable to current endodontic treatments.