Abstract
Thymic epithelial tumors are rare malignancies, that may be aggressive and difficult to treat, with variable prognosis. The histopathological classification distinguishes two major tumor types: thymomas and thymic carcinomas. Autoimmune manifestations (with myasthenia gravis as the most common) are observed in nearly one third of patients at diagnosis.Assessing the resectability of the tumor represents the first stage of the therapeutic strategy, as complete resection is the most significant prognostic factor on patient survival. If complete resection seems possible upfront, surgery is the first step of the treatment, and is possibly followed by postoperative radiotherapy. For unresectable thymic tumors, pre-treatment biopsy is performed, and treatment is then based on induction chemotherapy followed by surgical resection or radiotherapy. Patients with no eligibility to focal treatment receive chemotherapy alone.Following a call of the French National Cancer Institute, a network of expert centers for the management of thymic malignancies started in 2012: RYTHMIC.1877-1203/© 2023 SPLF. Published by Elsevier Masson SAS. All rights reserved.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
