Abstract

Vacuolar hepatopathies include a heterogeneous group of so-called overloading hepatopathies. Their diagnosis is based on histological criteria, such as hepatocyte swelling resulting in cytomegaly with vacuolated and reticulated cytoplasm. Vacuolar hepatopathy is often idiopathic. Its development can be secondary to a simple reactive hepatopathy, and include numerous associated conditions. Endogenous or exogenous hypercorticism is the most common cause of vacuolar hepatopathy in dogs. The frequency and complications of idiopathic vacuolar hepatopathy in Scottish terriers suggest a breed and familial predisposition.

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