Abstract

Objective: EEC alone or co-cultured with human embryos express leptin and leptin receptor (JCEM, 2000) and IL-1 up-regulates leptin secretion by EEC but not by endometrial stromal cells (ESC) (Fertil Steril, 2000). In the present investigation the effects of leptin on the expression of β3 integrin were investigated and compared with IL-1β effects. IL-1β regulatory effects on leptin and leptin receptor expression at protein level in EEC and ESC cultures were also assessed.

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