Abstract
Objectives: to investigate macro-regional disparities in the incidence of leprosy in children and adolescents under 15 years old in Brazil from 2001 to 2022, with a focus on leprosy-related disabilities. Methods: an ecological study was carried out with data from the Brazilian Notifiable Diseases Information System (SINAN). The annual number of leprosy cases was normalized to every 100,000 residents in each macro-region (incidence), stratified by leprosy-related disability (grade 0, 1 and 2). The significance level was set at 5%, and Poisson regression adjusted for a robust dispersion was used to estimate the incidence ratio. Results: approximately 14% (7,694) of all leprosy cases in this age group were notified with grade 1 (78.9%) or 2 (21.1%) disability. Moreover, in grade 1 and 2, the incidence of leprosy was significantly higher in the North, Northeast and Central-West macro-regions when compared to the national estimate, as well as significantly lower in the Southeast and South (p-value <0.05). Conclusion: macro-regional disparities were observed in the incidence of leprosy in children and adolescents under 15 years old with grade 1 or 2 disability in Brazil from 2001 to 2022.
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