Abstract
We studied the effect of transpupillary thermotherapy (TTT) by a diode laser at 810 nm combined with episcleral ruthenium-106 plaque treatment (<sup>106</sup>Ru) on lens transparency in patients with choroidal melanoma. Lens transmission of blue-green light was measured by fluorophotometry in 17 patients treated with <sup>106</sup>Ru treatment and TTT (measured 0.3–6 years after treatment), 12 patients treated with <sup>106</sup>Ru alone (measured 1–9 years after treatment) and 25 age-matched healthy controls. Differences in lens transmission were not significant between treated and untreated fellow eyes (p > 0.15) nor between patient and control eyes (p > 0.25). TTT of choroidal melanoma combined with <sup>106</sup>Ru plaque irradiation did not have a significant effect on the lens transparency up to 6 years after treatment.
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