Abstract
BackgroundTo evaluate the distribution of lens thickness (LT) and its associations with other ocular biometric factors among cataract patients in Shanghai.MethodsTwenty-four thousand thirteen eyes from 24,013 cataract patients were retrospectively included. Ocular biometric factors including LT, central corneal thickness (CCT), anterior chamber depth (ACD), white-to-white (WTW) distance, anterior corneal curvature, and axial length (AL) were obtained using the IOLMaster700. The associations between LT and general or ocular factors were assessed.ResultsThe mean age was 62.5 ± 13.6 years and 56.1% were female. The mean LT was 4.51 ± 0.46 mm. The LT was greater in older patients (P < 0.001). LT was positively correlated with CCT, while negatively correlated with ACD, WTW, and anterior corneal curvature (P < 0.001). Multivariate analysis revealed that increased LT was associated with older age, male gender, thicker CCT, shallower ACD, larger WTW, and flatter anterior corneal curvature (P < 0.001). LT changed with a variable behavior according to AL. In short eyes LT increased as AL increased, then decreased with longer AL in normal eyes and moderate myopic eyes, but increased again as AL increased in highly myopic eyes. Thickest LT was found in the 20.01–22 mm AL group. The correlation between LT and other biometric factors remained significant when stratified by ALs.ConclusionsIn a large Chinese cataractous population, we found that the thicker lens may be associated with older age, male gender, thicker CCT, shallower ACD, larger WTW, and flatter anterior corneal curvature. As AL increased, the change of LT was nonlinear, with the thickest lens seen in the 20–22 mm AL group.
Highlights
Cataract is one of the leading causes of visual impairment worldwide [1]
Based on the optical lowcoherence reflectometry (OLCR), an increased trend of lens thickness (LT) with cataract formation was identified [9], while based on swept source optical coherence tomography (SS-OCT), Henriquez et al found that the increase of LT was independent of lens density in mild to moderate cataract [10]
When LT was stratified by age, in either men or women, LT was significantly greater in older patients (KruskalWallis test, P < 0.001)
Summary
With the advancement of cataract surgery and intraocular lens (IOL) design, the accurate biometric measurement has become a crucial factor in surgical planning [2]. Lens thickness (LT) is one of the important parameters in ocular biometry. Not. Recently, accurate measurement of LT in cataractous eyes has become available due to the advancement of (2021) 8:22 optical biometry [9,10,11]. Based on the optical lowcoherence reflectometry (OLCR), an increased trend of LT with cataract formation was identified [9], while based on swept source optical coherence tomography (SS-OCT), Henriquez et al found that the increase of LT was independent of lens density in mild to moderate cataract [10]. To evaluate the distribution of lens thickness (LT) and its associations with other ocular biometric factors among cataract patients in Shanghai
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