Abstract
BackgroundWe report a case of IgE-mediated hypersensitivity to lemon seed. We demonstrate for the first time a pattern of cross-sensitisation between seeds of citrus hybrid species from similar ancestral species origins.Case reportDescribed is a case of a 26-year-old female with recurrent anaphylaxis on exposure to lemon seed with sensitisation shown on prick to prick testing. Prick to prick testing was also performed to a variety of citrus fruit seeds and edible foods from additional notable families of the Sapindale order.ConclusionIn cases of unexplained or recurrent anaphylaxis in adult patients, citrus seed allergy should be considered.
Highlights
We report a case of IgE-mediated hypersensitivity to lemon seed
Allergens identified within the citrus fruit seeds are citrin: a globulin seed storage protein, and albumin seed storage proteins [3]
We present the first adult case of lemon seed allergy with a demonstrable pattern of cross-sensitisation within the citrus fruit species
Summary
We report a case of IgE-mediated hypersensitivity to lemon seed. We demonstrate for the first time a pattern of cross-sensitisation between seeds of citrus hybrid species from similar ancestral species origins.Case report: Described is a case of a 26-year-old female with recurrent anaphylaxis on exposure to lemon seed with sensitisation shown on prick to prick testing. Conclusion: In cases of unexplained or recurrent anaphylaxis in adult patients, citrus seed allergy should be considered. We present the first adult case of lemon seed allergy with a demonstrable pattern of cross-sensitisation within the citrus fruit species. *Correspondence: Stephanie.Kayode@gstt.nhs.uk 1 Department of Adult Allergy, Guy’s and St Thomas’ NHS Foundation Trust, London SE1 9RT, UK Full list of author information is available at the end of the article symptoms resolved within 1 h with oral antihistamine and salbutamol inhalation.
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