Abstract
Abstract—Two cases of visceral leishmaniasis in patients with AIDS who showed «transepidermal elimination» are described below. In one of them, the parasite was observed in the keratinocytes along the entire epidermis and at all of its levels, independently from the eccrine sweat glands, and also inside the keratinocytes around the acrosyringia, inside the eccrine duct and eccrine gland cells, suggesting elimination of leishmania through the epidermal keratinocytes and the eccrine glands. In the other case, the parasite was found in the eccrine glands and ducts and in the keratinocytes around the acrosyringia, suggesting elimination through the eccrine sweat glands. This phenomenon is reviewed in infectious diseases as a whole and more specifically in the cases of leishmaniasis described.
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