Left ventricular motion quantification parameters from tissue phase mapped MRI: influence of gender

Jan Paul,Raphael Beck,Peter Bernhardt,Wolfgang Rottbauer,Heiko Neumann,Volker Rasche,Dominik Buckert

doi:10.1186/1532-429x-17-s1-q20

Jan Paul, Raphael Beck + Show 5 more

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https://doi.org/10.1186/1532-429x-17-s1-q20

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Abstract

Background Several motion parameters for quantification of LV motion abnormalities and asynchrony have been described in literature, but were investigated with different acquisition protocols and for different cohorts, thus impeding comparability. For derivation of normal values in healthy volunteers, calculation of all parameters from a single acquisition protocol is desirable. In this study, influence of gender on the motion parameters is investigated in order to determine the necessity of separate female/male normal values.

Highlights

Several motion parameters for quantification of LV motion abnormalities and asynchrony have been described in literature, but were investigated with different acquisition protocols and for different cohorts, impeding comparability
Influence of gender on the motion parameters is investigated in order to determine the necessity of separate female/male normal values
Acquisition parameters were: Philips Achieva 3 T, 32 channel cardiac coil, velocity encoded (Tissue Phase Mapped, TPM) segmented black-blood gradient echo with VENC=30 cm/s, TR/TE=6.1/4.6 ms, FOV adapted to patient size, resolution = 2x2x8 mm3, 3 k-lines/segment, SENSE=2, phase interval=30 ms, and nominal scan time=5:51 min:sec for 3 short axis slices

Summary

Background

Several motion parameters for quantification of LV motion abnormalities and asynchrony have been described in literature, but were investigated with different acquisition protocols and for different cohorts, impeding comparability. For derivation of normal values in healthy volunteers, calculation of all parameters from a single acquisition protocol is desirable. Influence of gender on the motion parameters is investigated in order to determine the necessity of separate female/male normal values. B) rotation-based: Base Apex Rotation Correlation [BARC]. C) strain-based: Temporal Uniformity of Strain [TUS], Standard Deviation of Onset/Peak Time [s (Tonset/peak)], Coefficient of Variation [CV], Difference between Septal and Lateral Peak Circumferential Strain [DiffSLpeakCS], Onset/Peak Of Shortening Delay [OS/PS Delay], Regional Variance of Strain [RVS], and Regional Variance Vector of Strain [RVVPS] B) rotation-based: Base Apex Rotation Correlation [BARC]. c) strain-based: Temporal Uniformity of Strain [TUS], Standard Deviation of Onset/Peak Time [s (Tonset/peak)], Coefficient of Variation [CV], Difference between Septal and Lateral Peak Circumferential Strain [DiffSLpeakCS], Onset/Peak Of Shortening Delay [OS/PS Delay], Regional Variance of Strain [RVS], and Regional Variance Vector of Strain [RVVPS]

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