Abstract
Left ventricular assist device for end-stage heart failure: results of the first LVAD destination program in the Netherlands : Towards LVAD destination therapy in the Netherlands?
Highlights
Today, heart transplantation is the golden standard for the treatment of patients with end-stage heart failure
left ventricular assist devices (LVADs) were used as a bridge to a transplantation (BTT) or bridge to recovery in the very few patients whose heart function improved after a period of mechanical support
In the United States the Heart Mate II has been approved for BTT since 2008 and as destination therapy since 2010, while HeartWare is approved as BTT since 2010 and is still awaiting approval for destination therapy
Summary
Heart transplantation is the golden standard for the treatment of patients with end-stage heart failure. LVADs were used as a bridge to a transplantation (BTT) or bridge to recovery in the very few patients whose heart function improved after a period of mechanical support. The complication rates have dropped considerably and an additional treatment for end-stage heart failure has become a reality, paving the way for LVAD as long-term therapy.
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