Left main coronary artery dimension and variation in Thai population

Abstract

Abstract Funding Acknowledgements Type of funding sources: None. Objectives The aim of our study was to determine the length, proximal and distal dimension of the left main coronary artery (LMCA) in Thai population with normal LMCA, from coronary computed tomography angiography (CCTA). Background The dimensions and length of the coronary artery are important to treatment planning and outcome prediction after revascularization. The previous studies showed that coronary artery dimensions are influenced by age, sex and BSA which may be effected by race. Recently, very limited data about coronary artery dimensions in general Thai population are available. Methods 560 patients who have undergone CCTA at a Thai hospital with normal coronary angiogram of LMCA and no history of previous percutaneous coronary interventions and coronary artery bypass graft surgery were included in the study. The LMCA cross-sectional dimensions were obtained at two points of each vessel: ostium and distal. The length of LMCA was studied. The baseline characteristics data of participants such as age, body weight, height body surface area (BMI) and body surface area (BSA) and the other findings of CCTA on the LMCA dimensions and length were evaluated. Results This study showed that the mean cross-sectional dimensions of the proximal and distal of LMCA were 3.89 ± 0.76 mm. and 3.4 ± 0.67 mm. respectively. The mean length of LMCA was 8.66 ± 3.69 mm. The dimension of vessels in males were significantly larger in size than females. The proximal and distal LMCA dimensions in males were 3.98 ± 0.81 mm. and 3.8 ± 0.69 mm. respectively. And the proximal and distal LMCA dimensions in females were 3.51 ± 0.72 mm. and 3.27 ± 0.59 mm. respectively. The factors of significant correlations were found with sex, height, weight, BMI, BSA, left dominant vessel and coronary artery calcium scores (CACs) on the proximal and distal dimensions of LMCA. In multivariate analysis, BSA and dominant system were showed significant correlation to the proximal dimension of LMCA, and BSA was showed significant correlation to the distal dimension of LMCA. The influences on length of LMCA were height, weight, BMI, BSA, right dominant vessel and CACs but no factors were significant correlation by multivariate analysis. Conclusions The length, proximal and distal dimensions of LMCA in general Thai population were differences from the previous studies which were studied in other nations. The influences on the dimensions of LMCA were sex, height, weight, BMI, BSA, left dominant vessel, and CACs. And the influences on the length of LMCA were height, weight, BMI, BSA, right dominant vessel and CACs.